Manual testing and automated testing are two major methodologies in software testing.

Manual testing is where the testers manually run test cases without any automation tool. Testers act as end-users and check if the application is working as it should. It is appropriate for exploratory, usability, and ad-hoc testing, where human intuition is required. It is time-consuming, error-prone, and not suitable for large-scale or repetitive testing.

Automated testing, conversely, relies on scripts and test tools to execute tests programmatically. It is quicker, more stable when it comes to regression testing, and is capable of executing tests multiple times with little effort. Automation works well in stable apps where tests are to be run often, i.e., in continuous integration and delivery pipelines.

In short, manual testing is suitable for flexibility and human eye observation, whereas automated testing is most suitable for speed, consistency, and scalability. A balanced approach to testing frequently employs both and balances quality with efficiency.
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